Read the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor, diabetes educator, or pharmacist.

Learn all preparation and usage instructions from your health care professional and the product package.

Before using, check this product visually for particles or discoloration. If either is present, do not use the insulin. Insulin glulisine should be clear and colorless.

Before injecting each dose, clean the injection site with rubbing alcohol. Change where you inject each time to lessen the risk of problems or damage under the skin (for example, pits/lumps or thickened skin). Insulin glulisine injection is for the stomach area, the thigh, or the back of the upper arm. Do not inject into skin that is red, swollen, itchy, or damaged. Do not inject cold insulin because this can be painful.

Inject this medication under the skin as directed by your doctor, usually within 15 minutes before eating a meal or within 20 minutes after starting the meal. Do not inject into a vein or muscle because very low blood sugar (hypoglycemia) may occur. Because this insulin is fast-acting, do not use the insulin if you are unable to eat within 15 minutes of injection or if you have low blood sugar. Not eating right after a dose of insulin may lead to low blood sugar (hypoglycemia). Do not rub the area after the injection.

Giving insulin glulisine into a vein should only be done by a health care professional. Very low blood sugar may result.

If you are directed to inject this insulin with an infusion pump, read the instruction manual and directions that come with the infusion pump. If you have any questions, ask your health care professional. Avoid exposing the pump or its tubing to direct sunlight or other heat sources. Do not dilute insulin if you are using an insulin pump.